Research into hypnosis in military applications is further verified by the Project MKULTRA experiments, also conducted by the CIA. According to Congressional testimony, the CIA experimented with utilizing LSD and hypnosis for mind control. Many of these programs were done domestically and on participants who were not informed of the study's purposes or that they would be given drugs.
Barber et al. noted that similar factors appeared to mediate the response both to hypnotism and to cognitive behavioural therapy, in particular systematic desensitization. Hence, research and clinical practice inspired by their interpretation has led to growing interest in the relationship between hypnotherapy and cognitive behavioural therapy.:105
Before long, hypnotism started finding its way into the world of modern medicine. The use of hypnotism in the medical field was made popular by surgeons and physicians like Elliotson and James Esdaille and researchers like James Braid who helped to reveal the biological and physical benefits of hypnotism. According to his writings, Braid began to hear reports concerning various Oriental meditative practices soon after the release of his first publication on hypnotism, Neurypnology (1843). He first discussed some of these oriental practices in a series of articles entitled Magic, Mesmerism, Hypnotism, etc., Historically & Physiologically Considered. He drew analogies between his own practice of hypnotism and various forms of Hindu yoga meditation and other ancient spiritual practices, especially those involving voluntary burial and apparent human hibernation. Braid's interest in these practices stems from his studies of the Dabistān-i Mazāhib, the "School of Religions", an ancient Persian text describing a wide variety of Oriental religious rituals, beliefs, and practices.
It is used for a wide variety of applications, and studies into its efficacy are often of poor quality which makes it difficult to determine efficacy. Several recent meta-analyses and systematic reviews of the literature on various conditions have concluded that the efficacy of hypnotherapy is "not verified", that there is no evidence or insufficient evidence for efficacy.